Dr. Hanna Gay, pediatric AIDS specialist
HIV Infection Returns To 'Cured' Child
Originally printed 7/10/2014 (Issue 2228 - Between The Lines News)
MISSISSIPPI - Federal Officials and Medical Professionals announced that a 46-month-old Mississippi girl, thought to have been cured of HIV, has significant levels of the virus in her bloodstream.
The Mississippi Baby, born to an HIV positive mother, is now being treated for rebound viremia, elevated HIV virus levels that often occur two to four weeks after HIV infection.
Last year, doctors celebrated the case with bated breath. They hoped that the intense level of administered drugs would keep the virus away in the first cure of HIV in a child. After 27 months of not receiving anti-viral therapy, the infant has rebounded with HIV viremia.
"Certainly, this is a disappointing turn of events for this young child, the medical staff involved in the child's care, and the HIV/AIDS research community," Anthony Fauci, director of the National Institute of Allergy and Infection Diseases, said at the briefing.
Hanna Gay, M. D., a pediatric HIV specialist at the University of Mississippi Medical Center in Jackson is the child's primary care doctor. Gay said that the child would return every six to eight weeks for regularly scheduled visits to check the HIV status. Gay, along with her staff, took blood tests at every visit but didn't notice any abnormalities; there was no gradual warning. There was no evidence of enlarged lymph nodes, no enlargement of spleen or liver. Until a recent check up, the girl seemed fine. But when tests came in that showed the girl's CD4 T-cell levels at 28 percent, doctors immediately took action.
"It felt very much like a punch to the gut," Gay stated in the briefing. "It was extremely disappointing but from the scientific findings I hope it will lead to bigger and better things."
Since being administered HIV prophylactic drugs, the 46-month-old's viral levels have fallen by 75 percent of what they were when first detected.
The child's mother was diagnosed with HIV while pregnant. Within 30 hours of birth, the Mississippi baby was given a faster and stronger treatment than usual, before tests even confirmed that the child was, indeed, HIV positive.
The child underwent treatment for 18 months. After being lost to follow-up, she and her mother then came back to the University of Mississippi Medical Center, and the girl was found to have no trace of the HIV virus in the bloodstream. No anti-viral HIV treatment was administered for 27 months. This treatment set a scientific precedent, as all previous cases were off the treatment drugs for months instead of years.
Until doctors find a permanent cure, the girl will be on antiviral prophylactic therapy for the rest of her life.
"Hopefully in the next ten years we will learn how to control the virus rebound from reservoirs so treatment doesn't have to be lifelong," Professor of Infectious Diseases, Johns Hopkins Children's Center, Baltimore, Deborah Persaud said. Persaud is one of two pediatric HIV experts involved in the ongoing analysis of the young girl's case.
"The fact that this child was able to remain off antiretroviral treatment for two years and maintain quiescent virus for that length of time is unprecedented," Persaud said. "Typically, when treatment is stopped, HIV levels rebound within weeks, not years."
- Mark Totten Seeks Attorney General Seat, Speaks On Schuette
- MSHDA Under Investigation, Snyder Fundraiser Raises Questions
- ACLU Dinner Honors Local Heroes
- Masquerave At ARTLABJ And Saginaw
- Coming Out With Self and With Michigan
- Michigan For Marriage Community Conversation
- A Solid LGBT Ally In Peters
- Gary Peters Releases Statement On SCOTUS Decision
- Marriage 'Decision Day' Gatherings To Be Held Throughout State
- Macomb County Extends LGBT Protections To Employees
- LGBT Bowling Tournament Strikes Metro Detroit
- Kalamazoo Says Goodbye To A Community Icon
- BREAKING: National Republicans Pull Nearly $1 Million In Advertising For Land
- Last Detroit Mattachine Society Officer Comes To Ann Arbor
- Washtenaw County Bar Association Reaches Out To Area LGBTs
- Terri Lynn Land Reminds Facebook She Is a Mom
- National Republicans Pull Nearly $1 Million In Advertising For Land
- All Eyes On Michigan As SCOTUS Refuses To Hear Marriage Equality Cases
- The Accidental Activists Of Ann Arbor's Homoplex
- AIDS/HIV Organizations
- Detroit Department of Health and Wellness Promotion - HIV/AIDS PROGRAMS
- AIDS Foundation of Chicago
- Ed Schmid Ford
- Bridal Gowns
- B. Ella Bridal
- Carpet Cleaning
- Hagopian Cleaning Services
- MGM Grand Detroit
- Pet Boarding
- Happy Hounds Dog Day Care
- Namaste Yoga
Enter contests to win great prizes like CDs, DVDs, concert tickets and more
Sign up to receive our weekly newsletters today!
Travis Parman predicted the future. As the current director of Corporate Communications at Nissan, Parman oversees all sorts of relationships within the automotive industry. But it wasn't that long ago that he wrote a 333-page thesis for his master's degree that specifically examined the relationship between corporations, their media marketing strategies and the LGBT community at large.View More Automotive
This Week's Issue
Download or view this week's print issue today!
Sign up to receive our weekly newsletters today!